Cyclic AMP-Dependent Regulation of Kv7 Voltage-Gated Potassium Channels

Voltage-gated Kv7 potassium channels, encoded by KCNQ genes, have major physiological impacts cardiac myocytes, neurons, epithelial cells, and smooth muscle cells. Cyclic adenosine monophosphate (cAMP), a well-known intracellular secondary messenger, can activate numerous downstream effector protein...

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Bibliographic Details
Main Authors: Jennifer van der Horst, Iain A. Greenwood, Thomas A. Jepps
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Physiology
Subjects:
PKA
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00727/full