Optical Quantal Analysis Using Ca2+ Indicators: A Robust Method for Assessing Transmitter Release Probability at Excitatory Synapses by Imaging Single Glutamate Release Events
Despite evidence that presynaptic efficacy and plasticity influence circuit function and behavior in vivo, studies of presynaptic function remain challenging owing to the difficulty of assessing transmitter release in intact tissue. Electrophysiological analyses of transmitter release are indirect a...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-03-01
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| Series: | Frontiers in Synaptic Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fnsyn.2019.00005/full |