IFN-γ, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13
<p>Abstract</p> <p>Background</p> <p>IL-13 is a critical mediator of allergic asthma and associated airway hyperresponsiveness. IL-13 acts through a receptor complex comprised of IL-13Rα1 and IL-4Rα subunits with subsequent activation of signal transducer and activator...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-12-01
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| Series: | Respiratory Research |
| Online Access: | http://respiratory-research.com/content/9/1/84 |