Intestinal stem cell-derived enteroids from morbidly obese patients preserve obesity-related phenotypes: Elevated glucose absorption and gluconeogenesis

Intestinal stem cell-derived enteroids from morbidly obese patients preserve obesity-related phenotypes: Elevated glucose absorption and gluconeogenesis

Objective: The mechanisms behind the efficacy of bariatric surgery (BS) for treating obesity and type 2 diabetes, particularly with respect to the influence of the small bowel, remain poorly understood. In vitro and animal models are suboptimal with respect to their ability to replicate the human in...

Full description

Bibliographic Details
Main Authors: Nesrin M. Hasan, Kelli F. Johnson, Jianyi Yin, Nicholas W. Baetz, Lea Fayad, Vadim Sherman, Sarah E. Blutt, Mary K. Estes, Vivek Kumbhari, Nicholas C. Zachos, Olga Kovbasnjuk
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Molecular Metabolism
Subjects:
Human enteroids
Obesity
Bariatric surgery
Glucose absorption
Gluconeogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820302039

Internet

http://www.sciencedirect.com/science/article/pii/S2212877820302039

Similar Items