Effect of Alcohol Consumption during Antiretroviral Therapy on HIV-1 Replication: Role of Cytochrome P3A4 Enzyme

Effect of Alcohol Consumption during Antiretroviral Therapy on HIV-1 Replication: Role of Cytochrome P3A4 Enzyme

Alcohol consumption is prevalent in HIV/AIDS infected patients. It possesses serious effects on protease inhibitors (PIs), which are used as an antiviral drug. While taking PIs, the secretion of Cytochrome P3A4 (CYP3A4) enzymes occurs from the liver and it metabolizes the drug to CYP3A4-PI complex....

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Bibliographic Details
Main Authors: Srijita Mondal, Priyanka Ghosh, Dibyendu Biswas, Priti Kumar Roy
Format: Article
Language:English
Published: International Journal of Mathematical, Engineering and Management Sciences 2019-08-01
Series:International Journal of Mathematical, Engineering and Management Sciences
Subjects:
HIV/AIDS
Viral load
Alcohol consumption
CYP3A4 enzyme
Protease inhibitor
Online Access:https://www.ijmems.in/assets//73-IJMEMS-BM-08-Vol.%204,%20No.%204,%20922%E2%80%93935,%202019.pdf

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