Effect of Alcohol Consumption during Antiretroviral Therapy on HIV-1 Replication: Role of Cytochrome P3A4 Enzyme
Alcohol consumption is prevalent in HIV/AIDS infected patients. It possesses serious effects on protease inhibitors (PIs), which are used as an antiviral drug. While taking PIs, the secretion of Cytochrome P3A4 (CYP3A4) enzymes occurs from the liver and it metabolizes the drug to CYP3A4-PI complex....
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
International Journal of Mathematical, Engineering and Management Sciences
2019-08-01
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Series: | International Journal of Mathematical, Engineering and Management Sciences |
Subjects: | |
Online Access: | https://www.ijmems.in/assets//73-IJMEMS-BM-08-Vol.%204,%20No.%204,%20922%E2%80%93935,%202019.pdf |