A prospective multicenter assessor-blinded randomized controlled study to compare the efficacy of short versus long protocols of electroconvulsive therapy as an augmentation strategy to clozapine in patients with ultra-resistant schizophrenia (SURECT study)

A prospective multicenter assessor-blinded randomized controlled study to compare the efficacy of short versus long protocols of electroconvulsive therapy as an augmentation strategy to clozapine in patients with ultra-resistant schizophrenia (SURECT study)

Abstract Background Although clozapine is the most effective antipsychotic drug for treatment-resistant schizophrenia, it leads to a poor or partial response in 40 to 70% of patients. Augmentation of clozapine with electroconvulsive therapy (ECT) is a highly effective and relatively safe treatment f...

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Bibliographic Details
Main Authors: Virginie Moulier, Mohamed Wassim Krir, Marine Dalmont, SURECT Group, Olivier Guillin, Maud Rothärmel
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Trials
Subjects:
Electroconvulsive therapy
Ultra-resistant schizophrenia
Clozapine
Augmentation strategy
Randomized controlled trial
Online Access:https://doi.org/10.1186/s13063-021-05227-3

Internet

https://doi.org/10.1186/s13063-021-05227-3

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