Cellular and molecular mechanisms of chronic inflammation-associated organ fibrosis
Organ fibrosis is a pathological condition associated with chronic inflammatory diseases. In fibrosis, excessive deposition of extracellular matrix severely impairs tissue architecture and function, eventually resulting in organ failure. This process is mediated primarily by the induction of myofibr...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-04-01
|
| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00071/full |