Sex-specific reference intervals of hematologic and biochemical analytes in Sprague-Dawley rats using the nonparametric rank percentile method.

Hematologic and biochemical analytes of Sprague-Dawley rats are commonly used to determine effects that were induced by treatment and to evaluate organ dysfunction in toxicological safety assessments, but reference intervals have not been well established for these analytes. Reference intervals as p...

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Bibliographic Details
Main Authors: Qili He, Guoming Su, Keliang Liu, Fangcheng Zhang, Yong Jiang, Jun Gao, Lida Liu, Zhongren Jiang, Minwu Jin, Huiping Xie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5738108?pdf=render