Enrichment and Molecular Analysis of Breast Cancer Disseminated Tumor Cells from Bone Marrow Using Microfiltration.

PURPOSE:Molecular characterization of disseminated tumor cells (DTCs) in the bone marrow (BM) of breast cancer (BC) patients has been hindered by their rarity. To enrich for these cells using an antigen-independent methodology, we have evaluated a size-based microfiltration device in combination wit...

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Bibliographic Details
Main Authors: Sreeraj G Pillai, Peixuan Zhu, Chidananda M Siddappa, Daniel L Adams, Shuhong Li, Olga V Makarova, Pete Amstutz, Ryan Nunley, Cha-Mei Tang, Mark A Watson, Rebecca L Aft
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5271341?pdf=render