HMGA2 promotes vasculogenic mimicry and tumor aggressiveness by upregulating Twist1 in gastric carcinoma

HMGA2 promotes vasculogenic mimicry and tumor aggressiveness by upregulating Twist1 in gastric carcinoma

Abstract High mobility group protein A2 (HMGA2) is a transcription factor that plays an important role in the invasion and metastasis of gastric carcinoma (GC). The term vasculogenic mimicry (VM) refers to the unique ability of aggressive tumour cells to mimic the pattern of embryonic vasculogenic n...

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Bibliographic Details
Main Authors: Junying Sun, Baocun Sun, Ran Sun, Dongwang Zhu, Xiulan Zhao, Yanhui Zhang, Xueyi Dong, Na Che, Jing Li, Fang Liu, Nan Zhao, Yong Wang, Danfang Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02494-6

Internet

https://doi.org/10.1038/s41598-017-02494-6

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