Regulatory mechanisms of miR-145 expression and the importance of its function in cancer metastasis

MicroRNAs are post-transcriptional mediators of gene expression and regulation, which play influential roles in tumorigenesis and cancer metastasis. The expression of tumor suppressor miR-145 is reduced in various cancer cell lines, containing both solid tumors and blood malignancies. However, the r...

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Bibliographic Details
Main Authors: Tahereh Zeinali, Behzad Mansoori, Ali Mohammadi, Behzad Baradaran
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218341635