Cholesterol crystallization in model biles: effects of bile salt and phospholipid species composition1

Cholesterol in human bile is solubilized in micelles by (relatively hydrophobic) bile salts and phosphatidylcholine (unsaturated acyl chains at sn-2 position). Hydrophilic tauroursodeoxycholate, dipalmitoyl phosphatidylcholine, and sphingomyelin all decrease cholesterol crystal-containing zones in t...

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Bibliographic Details
Main Authors: Antonio Moschetta, Gerard P. vanBerge-Henegouwen, Piero Portincasa, Giuseppe Palasciano, Karel J. van Erpecum
Format: Article
Language:English
Published: Elsevier 2001-08-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520315789