Identification of protein lysine methylation readers with a yeast three-hybrid approach

Abstract Background Protein posttranslational modifications (PTMs) occur broadly in the human proteome, and their biological outcome is often mediated indirectly by reader proteins that specifically bind to modified proteins and trigger downstream effects. Particularly, many lysine methylation sites...

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Bibliographic Details
Main Authors: Agnieszka Anna Rawłuszko-Wieczorek, Franziska Knodel, Raluca Tamas, Arunkumar Dhayalan, Albert Jeltsch
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-018-0175-3