NLRP3 Inflammasome Activation Is Involved in LPA<sub>1</sub>-Mediated Brain Injury after Transient Focal Cerebral Ischemia

NLRP3 Inflammasome Activation Is Involved in LPA<sub>1</sub>-Mediated Brain Injury after Transient Focal Cerebral Ischemia

Lysophosphatidic acid receptor 1 (LPA<sub>1</sub>) contributes to brain injury following transient focal cerebral ischemia. However, the mechanism remains unclear. Here, we investigated whether nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3 (NLRP...

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Bibliographic Details
Main Authors: Chi-Ho Lee, Arjun Sapkota, Bhakta Prasad Gaire, Ji Woong Choi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
LPA<sub>1</sub>
transient middle cerebral artery occlusion
NLRP3 inflammasome
bone marrow-derived macrophage
LPA
lipopolysaccharide
Online Access:https://www.mdpi.com/1422-0067/21/22/8595

Internet

https://www.mdpi.com/1422-0067/21/22/8595

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