Addition of aliskiren to olmesartan ameliorates tubular injury in chronic kidney disease patients partly by reducing proteinuria

Introduction : Tubular injury is more important than glomerulopathy for renal prognosis in chronic kidney disease (CKD) patients. Numerous studies have demonstrated the active participation of the renin–angiotensin system (RAS) in CKD. However, whether addition of aliskiren, a direct renin inhibitor...

Full description

Bibliographic Details
Main Authors: Tsukasa Nakamura, Eiichi Sato, Mayuko Amaha, Yasuhiro Kawagoe, Sayaka Maeda, Sho-ichi Yamagishi
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2012-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320311422580