Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

<p>Abstract</p> <p>Background</p> <p>Malignant ovarian disease is characterised by high rates of mortality due to high rates of recurrent chemoresistant disease. Anecdotal evidence indicates this may be due to chemoresistant properties of cancer stem cells (CSCs). Howev...

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Bibliographic Details
Main Authors: Gallagher Michael F, Heffron Cynthia CBB, Laios Alexandros, O'Toole Sharon A, Ffrench Brendan, Smyth Paul C, Flavin Richard J, Elbaruni Salah A, Spillane Cathy D, Martin Cara M, Sheils Orla M, O'Leary John J
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
chemoresistance
recurrent disease
cancer stem cell
p53
p21
Online Access:http://www.ovarianresearch.com/content/5/1/2

Internet

http://www.ovarianresearch.com/content/5/1/2

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