Cadmium down-regulates expression of XIAP at the post-transcriptional level in prostate cancer cells through an NF-κB-independent, proteasome-mediated mechanism

<p>Abstract</p> <p>Background</p> <p>Cadmium has been classified as a human carcinogen, affecting health through occupational and environmental exposure. Cadmium has a long biological half-life (>25 years), due to the flat kinetics of its excretion. The prostate is o...

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Bibliographic Details
Main Authors: Fox Eric, Kaplan David J, Kutikov Alexander, Uzzo Robert G, Makhov Peter, Golovine Konstantin, Kolenko Vladimir M
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/183