Uncovering Transcriptional Regulatory Networks by Sparse Bayesian Factor Model
<p>Abstract</p> <p>The problem of uncovering transcriptional regulation by transcription factors (TFs) based on microarray data is considered. A novel Bayesian sparse correlated rectified factor model (BSCRFM) is proposed that models the unknown TF protein level activity, the corre...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2010-01-01
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Series: | EURASIP Journal on Advances in Signal Processing |
Online Access: | http://asp.eurasipjournals.com/content/2010/538919 |