Uncovering Transcriptional Regulatory Networks by Sparse Bayesian Factor Model

<p>Abstract</p> <p>The problem of uncovering transcriptional regulation by transcription factors (TFs) based on microarray data is considered. A novel Bayesian sparse correlated rectified factor model (BSCRFM) is proposed that models the unknown TF protein level activity, the corre...

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Bibliographic Details
Main Authors: Qi Yuan(Alan), Chen Yidong, Meng Jia, Zhang Jianqiu(Michelle), Huang Yufei
Format: Article
Language:English
Published: SpringerOpen 2010-01-01
Series:EURASIP Journal on Advances in Signal Processing
Online Access:http://asp.eurasipjournals.com/content/2010/538919