BST2/Tetherin Inhibition of Alphavirus Exit

Alphaviruses such as chikungunya virus (CHIKV) and Semliki Forest virus (SFV) are small enveloped RNA viruses that bud from the plasma membrane. Tetherin/BST2 is an interferon-induced host membrane protein that inhibits the release of many enveloped viruses via direct tethering of budded particles t...

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Bibliographic Details
Main Authors: Yaw Shin Ooi, Mathieu Dubé, Margaret Kielian
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/7/4/2147