Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo

Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo

Cervical cancer remains one of the main factors leading to tumor-related death worldwide. Many strategies of cancer treatment such as chemotherapy are developed and used nowadays. However, for the cancer chemotherapy resistance, reduction of the limitation of cancer chemotherapy efficacy is one of t...

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Bibliographic Details
Main Authors: Yudi Xiong, Tianqi Li, Ganiou Assani, Huan Ling, Qian Zhou, Yangyang Zeng, Fuxiang Zhou, Yunfeng Zhou
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Cervical cancer
CDK4
CDK6
Ribociclib
Cell cycle
Cell apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218377424

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http://www.sciencedirect.com/science/article/pii/S0753332218377424

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