Altered GH-IGF-1 Axis in Severe Obese Subjects is Reversed after Bariatric Surgery-Induced Weight Loss and Related with Low-Grade Chronic Inflammation

Altered GH-IGF-1 Axis in Severe Obese Subjects is Reversed after Bariatric Surgery-Induced Weight Loss and Related with Low-Grade Chronic Inflammation

Endocrine disorders are common in obesity, including altered somatotropic axis. Obesity is characterized by reduced growth hormone (GH) secretion, although the insulin-like growth factor-1 (IGF-1) values are controversial. The aim of this study was to evaluate the effect of weight loss after bariatr...

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Bibliographic Details
Main Authors: Paula Juiz-Valiña, Lara Pena-Bello, Maria Cordido, Elena Outeiriño-Blanco, Sonia Pértega, Barbara Varela-Rodriguez, Maria Jesus Garcia-Brao, Enrique Mena, Susana Sangiao-Alvarellos, Fernando Cordido
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Journal of Clinical Medicine
Subjects:
obesity
bariatric surgery
endocrine disorders
somatotropic axis
GH
IGF-1
Online Access:https://www.mdpi.com/2077-0383/9/8/2614

Internet

https://www.mdpi.com/2077-0383/9/8/2614

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