Systemic autoinflammation with intractable epilepsy managed with interleukin-1 blockade

Abstract Background Autoinflammatory disorders are distinguished by seemingly random episodes of systemic hyperinflammation, driven in particular by IL-1. Recent pre-clinical work has shown a key role for IL-1 in epilepsy in animal models, and therapies for autoinflammation including IL-1 blockade a...

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Bibliographic Details
Main Authors: Allen D. DeSena, Thuy Do, Grant S. Schulert
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12974-018-1063-2