Preparation and scale up of extended-release tablets of bromopride

Preparation and scale up of extended-release tablets of bromopride

Reproducibility of the tablet manufacturing process and control of its pharmaceutics properties depends on the optimization of formulation aspects and process parameters. Computer simulation such as Design of Experiments (DOE) can be used to scale up the production of this formulation, in particular...

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Bibliographic Details
Main Authors: Guilherme Neves Ferreira, Marcos Giovani Rodrigues Silva, Aline Guerra Manssour Fraga, Luiz Cláudio Rodrigues Pereira da Silva, Luiz Marcelo Lira, Carlos Rangel Rodrigues, Helena Carla Castro, Valéria Pereira de Sousa, Lucio Mendes Cabral
Format: Article
Language:English
Published: Universidade de São Paulo 2014-04-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Bromoprida/comprimidos de liberação prolongada
Planejamento de experimentos
Compressão direta
Comprimidos de liberação prolongada/obtenção em escala aumentada
Comprimidos/cinética de liberação
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000200291&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000200291&lng=en&tlng=en

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