A single-nucleotide polymorphism of human neuropeptide s gene originated from Europe shows decreased bioactivity.

Using accumulating SNP (Single-Nucleotide Polymorphism) data, we performed a genome-wide search for polypeptide hormone ligands showing changes in the mature regions to elucidate genotype/phenotype diversity among various human populations. Neuropeptide S (NPS), a brain peptide hormone highly conser...

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Bibliographic Details
Main Authors: Cheng Deng, Ximiao He, Aaron J W Hsueh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3873911?pdf=render