Dominant-negative CK2alpha induces potent effects on circadian rhythmicity.

Circadian clocks organize the precise timing of cellular and behavioral events. In Drosophila, circadian clocks consist of negative feedback loops in which the clock component PERIOD (PER) represses its own transcription. PER phosphorylation is a critical step in timing the onset and termination of...

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Bibliographic Details
Main Authors: Elaine M Smith, Jui-Ming Lin, Rose-Anne Meissner, Ravi Allada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2211540?pdf=render