Evaluation of freely available software tools for untargeted quantification of 13C isotopic enrichment in cellular metabolome from HR-LC/MS data

13C Metabolic Flux Analysis (13C-MFA) involves the quantification of isotopic enrichment in cellular metabolites and fitting the resultant data to the metabolic network model of the organism. Coverage and resolution of the resultant flux map depends on the total number of metabolites and fragments i...

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Bibliographic Details
Main Authors: Manohar C. Dange, Vivek Mishra, Bratati Mukherjee, Damini Jaiswal, Murtaza S. Merchant, Charulata B. Prasannan, Pramod P. Wangikar
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Metabolic Engineering Communications
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214030119300203