Response to comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'
In 2016, we reported four substantial observations of APECED/APS1 patients, who are deficient in AIRE, a major regulator of central T cell tolerance (Meyer et al., 2016). Two of those observations have been challenged. Specifically, ‘private’ autoantibody reactivities shared by only a few patients b...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-06-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/45826 |