Response to comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'

In 2016, we reported four substantial observations of APECED/APS1 patients, who are deficient in AIRE, a major regulator of central T cell tolerance (Meyer et al., 2016). Two of those observations have been challenged. Specifically, ‘private’ autoantibody reactivities shared by only a few patients b...

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Bibliographic Details
Main Authors: Christina Hertel, Dmytro Fishman, Anna Lorenc, Annamari Ranki, Kai Krohn, Pärt Peterson, Kai Kisand, Adrian Hayday
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/45826