Fatty Acid Synthesis and Degradation Interplay to Regulate the Oxidative Stress in Cancer Cells

Fatty Acid Synthesis and Degradation Interplay to Regulate the Oxidative Stress in Cancer Cells

Both cytosolic fatty acid synthesis (FAS) and mitochondrial fatty acid oxidation (FAO) have been shown to play a role in the survival and proliferation of cancer cells. This study aimed to confirm experimentally whether FAS and FAO coexist in breast cancer cells (BCC). By feeding cells with 13C-labe...

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Bibliographic Details
Main Authors: Valeryia Mikalayeva, Ieva Ceslevičienė, Ieva Sarapinienė, Vaidotas Žvikas, Vytenis Arvydas Skeberdis, Valdas Jakštas, Sergio Bordel
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
cancer
metabolism
lipids
oxidative stress
metabolic flux analysis
Online Access:http://www.mdpi.com/1422-0067/20/6/1348

Internet

http://www.mdpi.com/1422-0067/20/6/1348

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