A universal reporter cell line for bioactivity evaluation of engineered cytokine products

Abstract Engineered cytokine products represent a growing class of therapeutic proteins which need to be tested for biological activity at various stages of pharmaceutical development. In most cases, dedicated biological assays are established for different products, in a process that can be time-co...

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Bibliographic Details
Main Authors: Jacqueline Mock, Christian Pellegrino, Dario Neri
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-60182-4