Informed switching strongly decreases the prevalence of antibiotic resistance in hospital wards.

Antibiotic resistant nosocomial infections are an important cause of mortality and morbidity in hospitals. Antibiotic cycling has been proposed to contain this spread by a coordinated use of different antibiotics. Theoretical work, however, suggests that often the random deployment of drugs ("m...

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Bibliographic Details
Main Authors: Roger D Kouyos, Pia Abel Zur Wiesch, Sebastian Bonhoeffer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21390265/?tool=EBI