Electrostatically biased binding of kinesin to microtubules.

The minimum motor domain of kinesin-1 is a single head. Recent evidence suggests that such minimal motor domains generate force by a biased binding mechanism, in which they preferentially select binding sites on the microtubule that lie ahead in the progress direction of the motor. A specific molecu...

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Bibliographic Details
Main Authors: Barry J Grant, Dana M Gheorghe, Wenjun Zheng, Maria Alonso, Gary Huber, Maciej Dlugosz, J Andrew McCammon, Robert A Cross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3226556?pdf=render