Electrostatically biased binding of kinesin to microtubules.
The minimum motor domain of kinesin-1 is a single head. Recent evidence suggests that such minimal motor domains generate force by a biased binding mechanism, in which they preferentially select binding sites on the microtubule that lie ahead in the progress direction of the motor. A specific molecu...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-11-01
|
Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC3226556?pdf=render |