In vivo Pharmacokinetic and Pharmacodynamic (PK/PD) Modeling and Establishment of the PK/PD Cutoff of Florfenicol Against Pasteurella multocida in Ducks

In vivo Pharmacokinetic and Pharmacodynamic (PK/PD) Modeling and Establishment of the PK/PD Cutoff of Florfenicol Against Pasteurella multocida in Ducks

Pasteurella multocida can invade and translocate through endothelial cells and result in vascular-system infection, which can cause severe economic losses in the poultry industry. Antibacterial therapy (especially florfenicol) plays an important part in controlling P. multocida infection. To preserv...

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Bibliographic Details
Main Authors: Xia Xiao, Weixuan Lan, Yaqin Zhao, Ruichao Li, Yuan Liu, Juan Liu, Zhiqiang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Microbiology
Subjects:
florfenicol
P. multocida
PK/PD modeling
PK/PD cutoff
dose
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.616685/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.616685/full

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