Analysis of epistatic interactions and fitness landscapes using a new geometric approach

<p>Abstract</p> <p>Background</p> <p>Understanding interactions between mutations and how they affect fitness is a central problem in evolutionary biology that bears on such fundamental issues as the structure of fitness landscapes and the evolution of sex. To date, ana...

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Bibliographic Details
Main Authors: Elena Santiago F, Sturmfels Bernd, Pachter Lior, Beerenwinkel Niko, Lenski Richard E
Format: Article
Language:English
Published: BMC 2007-04-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/7/60