Does upregulated host cell receptor expression provide a link between bacterial adhesion and chronic respiratory disease?

Abstract Expression of the platelet-activating factor receptor is upregulated in the respiratory epithelium of smokers and chronic obstructive pulmonary disease patients. We have recently determined that increased expression of PAFr correlates with higher levels of adhesion to human bronchial epithe...

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Bibliographic Details
Main Authors: Ronan F. O’Toole, Shakti D. Shukla, Eugene H. Walters
Format: Article
Language:English
Published: BMC 2016-10-01
Series:Journal of Translational Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12967-016-1063-x