Tau and mTOR: The Hotspots for Multifarious Diseases in Alzheimer's Development

Tau and mTOR: The Hotspots for Multifarious Diseases in Alzheimer's Development

The hyperphosphorylation of tau protein and the overexpression of mTOR are considered to be the driving force behind Aβ plaques and Neurofibrillay Tangles (NFT's), hallmarks of Alzheimer's disease (AD). It is now evident that miscellaneous diseases such as Diabetes, Autoimmune diseases, Ca...

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Bibliographic Details
Main Authors: Zeba Mueed, Pallavi Tandon, Sanjeev Kumar Maurya, Ravi Deval, Mohammad A. Kamal, Nitesh Kumar Poddar
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer's disease (AD)
tau
mTOR
Aβ plaques
Aβ modulators
hyperphosphorylation
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.01017/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.01017/full

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