Liposomal paclitaxel induces apoptosis, cell death, inhibition of migration capacity and antitumoral activity in ovarian cancer

Liposomal paclitaxel induces apoptosis, cell death, inhibition of migration capacity and antitumoral activity in ovarian cancer

The main goal of this study is to evaluate the efficacy of the paclitaxel (PTX) drug formulated with a liposomal nanosystem (L-PTX) in a peritoneal carcinomatosis derived from ovarian cancer. In vitro cell viability studies with the human ovarian cancer line A2780 showed a 50% decrease in the inhibi...

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Bibliographic Details
Main Authors: Raquel Santos Faria, Luiza Ianny de Lima, Raphael Severino Bonadio, João Paulo Figueiró Longo, Marjorie Coimbra Roque, João Nunes de Matos Neto, Sergio Enrique Moya, Mônica Cristina de Oliveira, Ricardo Bentes Azevedo
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ovarian cancer
Peritoneal carcinomatosis
A2780 cell line
Liposomal formulations
Paclitaxel
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221007836

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http://www.sciencedirect.com/science/article/pii/S0753332221007836

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