ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy

ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy

Abstract Background Diabetic nephropathy (DN) is currently the leading cause of end-stage renal disease globally. The endothelial-to-mesenchymal transition (EndMT) of glomerular endothelial cells has been reported to play a crucial role in DN. As a specific form of epithelial-to-mesenchymal transiti...

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Bibliographic Details
Main Authors: Lihong Lu, Ziwen Zhong, Jiahui Gu, Ke Nan, Minmin Zhu, Changhong Miao
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Molecular Medicine
Subjects:
KMT5A
ets1
PFN2
EndMT
Diabetic nephropathy
Online Access:https://doi.org/10.1186/s10020-021-00339-7

Internet

https://doi.org/10.1186/s10020-021-00339-7

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