Pharmacokinetics, radiation dosimetry, acute toxicity and automated synthesis of [18F]AmBF3-TATE

Pharmacokinetics, radiation dosimetry, acute toxicity and automated synthesis of [18F]AmBF3-TATE

Abstract Introduction [18F]AmBF3-TATE is a somatostatin agonist that selectively binds to somatostatin receptor subtype 2 (SSTR2). For clinical translation, pharmacokinetics, radiation dosimetry, and acute toxicity of [18F]AmBF3-TATE were assessed with good laboratory practice (GLP) standards. Metho...

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Bibliographic Details
Main Authors: Joseph Lau, Jinhe Pan, Etienne Rousseau, Carlos F. Uribe, Sudhakara Reddy Seelam, Brent W. Sutherland, David M. Perrin, Kuo-Shyan Lin, François Bénard
Format: Article
Language:English
Published: SpringerOpen 2020-03-01
Series:EJNMMI Research
Subjects:
Positron emission tomography
Neuroendocrine tumors
AmBF3-TATE
Fluorine-18
Dosimetry
Toxicology
Online Access:http://link.springer.com/article/10.1186/s13550-020-0611-9

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http://link.springer.com/article/10.1186/s13550-020-0611-9

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