A DOG’s View of Fanconi Anemia: Insights from C. elegans

C. elegans provides an excellent model system for the study of the Fanconi Anemia (FA), one of the hallmarks of which is sensitivity to interstrand crosslinking agents. Central to our understanding of FA has been the investigation of DOG-1, the functional ortholog of the deadbox helicase FANCJ. Here...

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Bibliographic Details
Main Authors: Martin Jones, Ann Rose
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Anemia
Online Access:http://dx.doi.org/10.1155/2012/323721