Role of Mitogen Activated Protein Kinase Signaling in Parkinson’s Disease

Role of Mitogen Activated Protein Kinase Signaling in Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative disorder caused by insufficient dopamine production due to the loss of 50% to 70% of dopaminergic neurons. A shortage of dopamine, which is predominantly produced by the dopaminergic neurons within the substantia nigra, causes clinical sympto...

Full description

Bibliographic Details
Main Authors: Anastasiia Bohush, Grazyna Niewiadomska, Anna Filipek
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
ERK1/2
JNKs
mitochondrial dysfunction
neurodegeneration
neuro-inflammation
oxidative stress
p38 MAPKs
Parkinson’s disease
Online Access:http://www.mdpi.com/1422-0067/19/10/2973

Internet

http://www.mdpi.com/1422-0067/19/10/2973

Similar Items