Intracellular Analysis of the Interaction between the Human Papillomavirus Type 16 E6 Oncoprotein and Inhibitory Peptides.

Oncogenic types of human papillomaviruses (HPVs) cause cervical cancer and other malignancies in humans. The HPV E6 oncoprotein is considered to be an attractive therapeutic target since its inhibition can lead to the apoptotic cell death of HPV-positive cancer cells. The HPV type 16 (HPV16) E6-bind...

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Bibliographic Details
Main Authors: Christina Stutz, Eileen Reinz, Anja Honegger, Julia Bulkescher, Johannes Schweizer, Katia Zanier, Gilles Travé, Claudia Lohrey, Karin Hoppe-Seyler, Felix Hoppe-Seyler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4495056?pdf=render