Type‐2 airway inflammation in mild asthma patients with high blood eosinophils and high fractional exhaled nitric oxide

Abstract Type‐2 (T2) inflammation is a characteristic feature of asthma. Biological therapies have been developed to target T2‐inflammation in asthma. IL‐13 is a key component of T2‐inflammation in asthma, driving mucus hypersecretion, IgE‐induction, and smooth muscle contraction. Early phase clinic...

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Bibliographic Details
Main Authors: Thomas Southworth, Marleen Van Geest, Dave Singh
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13078