A systematic flux analysis approach to identify metabolic vulnerabilities in human breast cancer cell lines
Abstract Background Increased flux through both glycolytic and oxidative metabolic pathways is a hallmark of breast cancer cells and is critical for their growth and survival. As such, targeting this metabolic reprograming has received much attention as a potential treatment approach. However, the h...
Main Authors: | Sheree D. Martin, Sean L. McGee |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | Cancer & Metabolism |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40170-019-0207-x |
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