A Rationally Designed Histone Deacetylase Inhibitor with Distinct Antitumor Activity against Ovarian Cancer

Histone deacetylase inhibitors (HDACIs) are a class of antineoplastic agents previously demonstrating preclinical chemosensitizing activity against drug-resistant cancer cells and mouse xenografts. However, whereas clinical studies have shown efficacy against human hematologic malignancies, solid t...

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Bibliographic Details
Main Authors: Ya-Ting Yang, Curt Balch, Samuel K. Kulp, Michael R. Mand, Kenneth P. Nephew, Ching-Shih Chen
Format: Article
Language:English
Published: Elsevier 2009-06-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558609801127