Trichinella spiralis Paramyosin Binds Human Complement C1q and Inhibits Classical Complement Activation.

BACKGROUND:Trichinella spiralis expresses paramyosin (Ts-Pmy) as a defense mechanism. Ts-Pmy is a functional protein with binding activity to human complement C8 and C9 and thus plays a role in evading the attack of the host's immune system. In the present study, the binding activity of Ts-Pmy...

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Bibliographic Details
Main Authors: Ran Sun, Xi Zhao, Zixia Wang, Jing Yang, Limei Zhao, Bin Zhan, Xinping Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4697845?pdf=render