Molecular mechanisms of template-independent RNA polymerization by tRNA nucleotidyltransferases

The universal 3'-terminal CCA sequence of tRNA is built and/or synthesized by the CCA-adding enzyme, CTP:(ATP) tRNA nucleotidyltransferase. This RNA polymerase has no nucleic acid template, but faithfully synthesizes the defined CCA sequence on the 3'-terminus of tRNA at one time, using CT...

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Bibliographic Details
Main Authors: Kozo eTomita, Seisueke eYamashita
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Genetics
Subjects:
CCA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00036/full