Differentiation of human pluripotent stem cells into functional airway basal stem cells
Summary: Airway basal cells play an essential role in the maintenance of the airway epithelium. Here, we provide a detailed directed differentiation protocol to generate ‘‘induced basal cells (iBCs)’’ from human pluripotent stem cells. iBCs recapitulate biological and functional properties of airway...
Main Authors: | Shingo Suzuki, Finn J. Hawkins, Cristina Barillà, Mary Lou Beermann, Darrell N. Kotton, Brian R. Davis |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | STAR Protocols |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166721003907 |
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