Role of Akt1 in renal fibrosis and tubular dedifferentiation during the progression of acute kidney injury to chronic kidney disease

Background/Aims Acute kidney injury (AKI) is an underestimated yet important risk factor for the development of chronic kidney disease (CKD), characterized by tubulointerstitial fibrosis and tubular dedifferentiation. Tubular dedifferentiation, which is associated with the loss of epithelial markers...

Full description

Bibliographic Details
Main Authors: Il Young Kim, Yeon Kyeong Park, Sang Heon Song, Eun Young Seong, Dong Won Lee, Sun Sik Bae, Soo Bong Lee
Format: Article
Language:English
Published: The Korean Association of Internal Medicine 2021-07-01
Series:The Korean Journal of Internal Medicine
Subjects:
Online Access:http://www.kjim.org/upload/pdf/kjim-2020-198.pdf