Strain Dependent Genetic Networks for Antibiotic-Sensitivity in a Bacterial Pathogen with a Large Pan-Genome.

The interaction between an antibiotic and bacterium is not merely restricted to the drug and its direct target, rather antibiotic induced stress seems to resonate through the bacterium, creating selective pressures that drive the emergence of adaptive mutations not only in the direct target, but in...

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Bibliographic Details
Main Authors: Tim van Opijnen, Sandra Dedrick, José Bento
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5015961?pdf=render